Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601216 | 1.00 | TYMP (0.43) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25955271 | 0.88 | ADORA3 (0.52) | SLC29A1ADORA1DPP4MEN1SLC28A1 | |
| SCHEMBL19344399 | 0.82 | TYMP (0.45) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12386194 | 0.82 | TYMP (0.45) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22343722 | 0.81 | SLC29A1 (0.35) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL24601222 | 0.81 | PDE4D (0.52) | PDE4DADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL20333764 | 0.81 | PDE4D (0.52) | PDE4DADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL24538657 | 0.80 | SLC29A1 (0.55) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7059620 | 0.80 | SLC29A1 (0.55) | TYMPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23586008 | 0.80 | AHCY (0.39) | TYMPADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137202-B1 | PROCESS FOR THE SYNTHESIS OF IB-MECA | CAN-FITE BIOPHARMA LTD (IL) | 2017-06-21 | — | — | EP | disclosed |