Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003277 | 0.88 | KMT2A (0.58) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL14476952 | 0.75 | KMT2A (0.67) | MAPTLMNAKMT2AMEN1RAB9A | |
| SCHEMBL14749157 | 0.75 | KMT2A (0.57) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL19003282 | 0.73 | TP53 (0.50) | MAPTLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL8110954 | 0.72 | GAA (0.75) | LMNAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2087572 | 0.72 | MEN1 (0.75) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL2087570 | 0.72 | MEN1 (0.75) | MAPTKMT2AMEN1RAB9AGAA | |
| SCHEMBL19003341 | 0.71 | KMT2A (0.53) | MAPTLMNAKMT2AMEN1RAB9A | |
| SCHEMBL31067939 | 0.69 | KMT2A (0.55) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL24496664 | 0.69 | GAA (0.69) | LMNAKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |