Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003277 | 0.82 | KMT2A (0.58) | KMT2AMAPTMEN1LMNACSNK2A1 | |
| SCHEMBL19003340 | 0.72 | TP53 (0.52) | KMT2AMAPTMEN1LMNAPSMD14 | |
| SCHEMBL19003276 | 0.71 | MAPT (0.55) | KMT2AMAPTMEN1LMNAPSMD14 | |
| SCHEMBL14730340 | 0.70 | MAPT (0.62) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL15859155 | 0.70 | MAPT (0.62) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL15859153 | 0.70 | MAPT (0.62) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL19003305 | 0.70 | MMP1 (0.63) | KMT2AMAPTMEN1LMNAHPGD | |
| SCHEMBL11936976 | 0.70 | MAPT (0.79) | KMT2AMAPTHPGDAPPALDH1A1 | |
| SCHEMBL15859149 | 0.69 | MAPT (0.74) | KMT2AMAPTMEN1LMNAPSMD14 | |
| SCHEMBL15859151 | 0.69 | MAPT (0.74) | KMT2AMAPTMEN1LMNAPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |