Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003268 | 0.82 | MAPT (0.47) | TP53KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19003275 | 0.81 | KMT2A (0.48) | TP53KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL19003340 | 0.81 | TP53 (0.52) | TP53KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL18985267 | 0.78 | MAPT (0.41) | TP53KMT2AMAPTMEN1PSMD14 | |
| SCHEMBL30758474 | 0.76 | KMT2A (0.51) | KDM4EKMT2AMAPTMEN1PSMD14 | |
| SCHEMBL19003277 | 0.75 | KMT2A (0.58) | KDM4EKMT2AMAPTMEN1PSMD14 | |
| SCHEMBL2863130 | 0.75 | LMNA (0.59) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL2863123 | 0.75 | LMNA (0.59) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL19003276 | 0.73 | MAPT (0.55) | KDM4EKMT2AMAPTMEN1PSMD14 | |
| SCHEMBL19003250 | 0.72 | MAPT (0.51) | TP53KDM4EKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |