Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003464 | 0.81 | EGFR (0.53) | MAPTTP53THRBSMN1; SMN2DHODH | |
| SCHEMBL19003315 | 0.80 | MAOB (0.50) | MAPTTP53MAOBMAOATHRB | |
| SCHEMBL19003456 | 0.77 | MAPT (0.48) | MAPTTP53MAOBMAOATHRB | |
| SCHEMBL15708821 | 0.75 | EPHX1 (0.68) | MAPTTP53THRBEPHX1EPHX2 | |
| SCHEMBL15709316 | 0.75 | EPHX1 (0.68) | MAPTTP53THRBEPHX1EPHX2 | |
| SCHEMBL19003273 | 0.74 | MEN1 (0.55) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL2955456 | 0.73 | EGFR (0.70) | MAPTTP53MAOBMAOAKDM4E | |
| SCHEMBL2681646 | 0.73 | EGFR (0.70) | MAPTTP53MAOBMAOAKDM4E | |
| SCHEMBL19003281 | 0.73 | KDR (0.56) | MAPTTP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL18985206 | 0.73 | TP53 (0.67) | MAPTTP53THRBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |