Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003461 | 0.90 | EGFR (0.54) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL18985281 | 0.81 | NAMPT (0.49) | MEN1KMT2AMAPTTP53EGFR | |
| SCHEMBL18985197 | 0.78 | MEN1 (0.55) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL18985289 | 0.77 | MAOB (0.64) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL19003308 | 0.76 | EGFR (0.54) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL19003273 | 0.75 | MEN1 (0.55) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL18985266 | 0.75 | HDAC8 (0.56) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL19003234 | 0.74 | MAPT (0.69) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL18985528 | 0.73 | NQO2 (0.56) | MEN1KMT2ANPC1LMNARAB9A | |
| SCHEMBL19003466 | 0.73 | NQO2 (0.56) | MEN1KMT2ANPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |