Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.59 |
| ▸ | TUBB | P07437 | 7/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003365 | 0.87 | TUBB1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12634285 | 0.83 | TUBB1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19003381 | 0.82 | TUBB1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12635492 | 0.82 | TUBB1 (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19003368 | 0.80 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4823325 | 0.79 | TUBB1 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7100310 | 0.79 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8270554 | 0.78 | PDE4A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9186213 | 0.78 | TUBB1 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL2327557 | 0.77 | TPMT (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106861-A1 | COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-22 | — | — | WO | disclosed |