SCHEMBL19003692

SCHEMBL19003692

CC1(C)OB(c2ccccc2-c2cccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c2)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 3/20 0.36
LPL P06858 2/20 0.36
NR1H2 P55055 3/20 0.32
NR1H3 Q13133 3/20 0.32
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
PDGFRB P09619 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16641537 0.85 LIPG (0.44) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL19003945 0.85 LIPG (0.44) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL19003972 0.85 LIPG (0.44) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL19003896 0.83 LIPG (0.46) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL16641536 0.80 LPL (0.41) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL16566414 0.80 LPL (0.41) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL21051655 0.79 LIPG (0.42) LIPGLPLPRMT5WDR77
SCHEMBL19107129 0.79 LIPG (0.53) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL19107131 0.79 LIPG (0.53) LIPGLPLPRMT5WDR77PDGFRB
SCHEMBL17722319 0.78 LPL (0.32) LIPGLPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017104946-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2017-06-22 WO disclosed