SCHEMBL1900372

SCHEMBL1900372

O=CCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 5/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
APP P05067 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612193 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL5411007 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL29248394 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL810347 0.95
Water SCHEMBL3993837 0.92
SCHEMBL2422200 0.86 ALDH1A1 (0.32) MEN1KMT2ATSHRALDH1A1TP53
SCHEMBL6656338 0.83
Methacrylic Acid SCHEMBL2484528 0.82 MEN1 (0.39) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL5411901 0.80 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL14190546 0.79 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3482740-B1 DENTAL PHOTOPOLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2024-03-27 EP claimed
US-6706025-B2 Lubricious catheters TARGET THERAPEUTICS, INC. 2004-03-16 US claimed
US-20170143841-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS KODIAK SCIENCES INC. 2017-05-25 US disclosed
US-9206291-B2 Hybrid compounds containing polysaccharide(s) and at least one polyoxyalkylene, method for preparing same, and applications thereof RHODIA OPERATIONS (FR) 2015-12-08 US disclosed
US-20140024776-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2014-01-23 US disclosed
US-8354460-B2 Matte clear coat enamel and substrates coated therewith PPG INDUSTRIES OHIO, INC. (US) 2013-01-15 US disclosed
US-20110105645-A1 MATTE CLEAR COAT ENAMEL AND SUBSTRATES COATED THEREWITH PPG INDUSTRIES OHIO, INC. (US) 2011-05-05 US disclosed
EP-2209815-A1 HYBRID COMPOUNDS CONTAINING POLYSACCHARIDE(S) AND AT LEAST ONE POLYOXYALKYLENE, METHOD FOR PREPARING SAME, AND APPLICATIONS THEREOF Rhodia Opérations (FR) 2010-07-28 EP disclosed
US-20100048738-A1 HYBRID COMPOUNDS BASED ON POLYOL(S) AND AT LEAST ONE OTHER MOLECULAR ENTITY, POLYMERIC OR NON-POLYMERIC, IN PARTICULAR OF THE POLYORGANOSILOXANE TYPE, PROCESS FOR THE PREPARATION THEREOF, AND APPLICATIONS THEREOF RHODIA OPERATIONS (FR) 2010-02-25 US disclosed
US-20090253609-A1 HYBRID COMPOUNDS BASED ON SILICONES, AND AT LEAST ONE OTHER MOLECULAR ENTITY, POLYMER OR OTHERWISE, ESPECIALLY OF THE POLYOL TYPE, METHOD FOR THE PREPARATION THEREOF, AND APPLICATIONS OF THE SAME RHODIA OPERATIONS (FR) 2009-10-08 US disclosed
WO-2009063082-A1 HYBRID COMPOUNDS CONTAINING POLYSACCHARIDE(S) AND AT LEAST ONE POLYOXYALKYLENE, METHOD FOR PREPARING SAME, AND APPLICATIONS THEREOF RHODIA OPERATIONS (FR) 2009-05-22 WO disclosed
US-20050068680-A1 Sliders bonded by a debondable nonstoichiometric encapsulant HITACHI GLOBAL STORAGE NETHERLANDS B.V. (NL) 2005-03-31 US disclosed
US-5976242-A OXYMETHYL-SUBSTITUTED ETHYLENEUREAS AXIM (FR) 1999-11-02 US disclosed
US-5563195-A BLEND OF A MODIFIED POLYOLEFIN AND BLOCKED ISOCYANATE NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-10-08 US disclosed
US-5559176-A WATER RESISTANCE NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-09-24 US disclosed
US-5534577-A ALKYLENE OXIDE TYPE SURFACTANT, REACTIVE ISOCYANATE, PAINTS, INKS, COATINGS, SEALANTS, ADHESIVES NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-07-09 US disclosed
US-4675374-A Solventless polymeric composition reaction product of (1) adduct of amine and acrylate with (2) polyacrylate NICHOLS GUS 1987-06-23 US disclosed
EP-0211978-A1 Method for preparing a solventless thermoset polymeric composition Nichols, Gus (US) 1987-03-04 EP disclosed
US-4547562-A Solventless polymeric composition comprising non arylamine, polyacrylate and epoxide NICHOLS GUS 1985-10-15 US disclosed
US-4438249-A Biodegradable polyurethane urea acyl semicarbazides for the manufacture of biodegradable alloimplants LIPATOVA TATYANA E (SU) 1984-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170143841-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS ACP1, PHOSPHO1, PARG MEN1 3080/4885KMT2A 2142/4885TSHR 4573/4885
US-20140024776-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS ACP1, PHOSPHO1, PARG MEN1 3080/4885KMT2A 2142/4885TSHR 4573/4885
US-20100048738-A1 HYBRID COMPOUNDS BASED ON POLYOL(S) AND AT LEAST ONE OTHER MOLECULAR ENTITY, POLYMERIC OR NON-POLYMERIC, IN PARTICULAR OF THE POLYORGANOSILOXANE TYPE, PROCESS FOR THE PREPARATION THEREOF, AND APPLICATIONS THEREOF PAOX, SQLE, SOST MEN1 917/4885KMT2A 1452/4885TSHR 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.