Sugi Predict

Sugi Predict / Compounds / SCHEMBL1900456

SCHEMBL1900456

SCHEMBL1900456

COc1ccc([N]c2ccc(OC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.65
▸ CA2 P00918 2/20 0.65
▸ CA7 P43166 2/20 0.65
▸ CA9 Q16790 2/20 0.65
▸ CA12 O43570 1/20 0.65
▸ CA14 Q9ULX7 1/20 0.65
▸ NOS3 P29474 2/20 0.56
▸ HTR3E A5X5Y0 1/20 0.56
▸ HTR3B O95264 1/20 0.56
▸ HTR3A P46098 1/20 0.56
▸ HTR3D Q70Z44 1/20 0.56
▸ HTR3C Q8WXA8 1/20 0.56
▸ ACHE P22303 1/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ TP53 P04637 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ TDP1 Q9NUW8 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ CYP2A6 P11509 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4392260 0.90 CA4 (0.59) CA1CA2CA7CA9CA12
SCHEMBL1405603 0.82 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL1405602 0.82 CA1 (0.65) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.80 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.80 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL1366759 0.80 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL13185916 0.78 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL156005 0.78 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL66886 0.78 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL10895835 0.78 CA1 (0.58) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 — — US claimed
EP-4240797-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS Rodenstock GmbH (DE) 2023-09-13 — — EP claimed
WO-2023135127-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS RODENSTOCK GMBH (DE) 2023-07-20 — — WO claimed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 — — US claimed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 — — US claimed
US-11286233-B2 Stilbene derivatives for the treatment of CNS and other disorders Ambient Photonics, Inc. (US) 2022-03-29 — — US claimed
EP-3807258-B1 PHOTOCHROMIC ANNELATED NAPHTHOPYRANE SYSTEMS WITH SPECIAL SUBSTITUENTS, FOR ATTAINING RAPID LIGHTENING SPEEDS RODENSTOCK GMBH (DE) 2021-10-20 — — EP claimed
US-20210114976-A1 Stilbene Derivatives for the Treatment of CNS and Other Disorders Ambient Photonics, Inc. (US) 2021-04-22 — — US claimed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 — — US claimed
EP-3621945-A1 STILBENE DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS Ambient Photonics, Inc. (US) 2020-03-18 — — EP claimed
US-7534853-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2009-05-19 — — US claimed
US-7094897-B2 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-08-22 — — US claimed
US-20060065890-A1 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-03-30 — — US claimed
EP-1379534-B1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-15 — — EP claimed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 — — US claimed
EP-1379534-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2004-01-14 — — EP claimed
WO-2002081488-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-10-17 — — WO claimed
EP-0469889-B1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LTD (GB) 1996-01-17 — — EP claimed
US-5189031-A Inhibitor of enzyme aldose reductase, useful in the treatment of certain peripheral effects of diabetes and galactosemia IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 — — US claimed
EP-0469889-A1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LIMITED (GB) 1992-02-05 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210114976-A1 Stilbene Derivatives for the Treatment of CNS and Other Disorders CLN6, MAPT, PSEN2 CA1 4265/4885CA2 4340/4885CA7 4680/4885
US-11286233-B2 Stilbene derivatives for the treatment of CNS and other disorders CLN6, MAPT, PSEN2 CA1 4265/4885CA2 4340/4885CA7 4680/4885
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 CA1 4332/4885CA2 3904/4885CA7 1919/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 CA1 4332/4885CA2 3904/4885CA7 1919/4885
US-20060065890-A1 Rhodium and iridium complexes RPIA, INPP5B, SIRT5 CA1 1991/4885CA2 369/4885CA7 683/4885
US-20040133004-A1 Rhodium and iridium complexes RPIA, SIRT5, INPP5B CA1 2352/4885CA2 415/4885CA7 862/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 CA1 4381/4885CA2 3642/4885CA7 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.