Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.30 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900465 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL30057341 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL3296001 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL18856153 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL10015241 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL3294716 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL16994826 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| SCHEMBL28627915 | 1.00 | THRB (0.32) | THRBLMNATDP1SPHK2SPHK1 | |
| Tetrahydrofuran SCHEMBL29115159 | 0.89 | — | — | |
| SCHEMBL13312833 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496593-B1 | AMPHIPHILIC COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME | UNIV YALE (US) | 2015-08-12 | — | — | EP | disclosed |
| US-9096630-B2 | Amphiphilic compositions and methods for preparing and using same | YALE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2496593-A2 | AMPHIPHILIC COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME | Yale University (US) | 2012-09-12 | — | — | EP | disclosed |
| US-20120225832-A1 | Amphiphilic Compositions and Methods for Preparing and Using Same | YALE UNIVERSITY (US) | 2012-09-06 | — | — | US | disclosed |
| WO-2011057192-A2 | AMPHIPHILIC COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME | YALE UNIVERSITY (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225832-A1 | Amphiphilic Compositions and Methods for Preparing and Using Same | UGCG, SGMS2, SGMS1 | THRB 4845/4885LMNA 266/4885TDP1 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.