SCHEMBL19004690

SCHEMBL19004690

C[C@H]1C=C(C(=O)c2ccccc2)C=CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 2/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PLA2G1B P04054 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
HPGD P15428 3/20 0.38
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SRD5A2 P31213 1/20 0.37
BCL2 P10415 1/20 0.36
MCL1 Q07820 1/20 0.36
RAB9A P51151 2/20 0.36
HPGDS O60760 1/20 0.36
ACHE P22303 1/20 0.36
CCR2 P41597 1/20 0.36
EZH2 Q15910 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599709 0.72 ALDH1A1 (0.34) ALDH1A1L3MBTL1GABRA1GABRB1MEN1
SCHEMBL18220718 0.72 ALDH1A1 (0.37) ALDH1A1L3MBTL1GABRA1GABRB1MEN1
SCHEMBL257363 0.69 ALDH1A1 (0.41) ALDH1A1L3MBTL1NPC1GABRA1GABRB1
SCHEMBL4242995 0.68 ALDH1A1 (0.48) ALDH1A1L3MBTL1NPC1MEN1KMT2A
SCHEMBL11227122 0.68 ALDH1A1 (0.39) ALDH1A1L3MBTL1NPC1GABRA1GABRB1
SCHEMBL23470770 0.66
SCHEMBL22175191 0.66 ALDH1A1 (0.45) ALDH1A1L3MBTL1NPC1MEN1KMT2A
SCHEMBL7905164 0.66 ALDH1A1 (0.45) ALDH1A1L3MBTL1NPC1GABRA1GABRB1
Benzophenone SCHEMBL7454682 0.64 ALDH1A1 (0.88) ALDH1A1L3MBTL1NPC1MEN1KMT2A
Benzophenone SCHEMBL30537001 0.63 ALDH1A1 (1.00) ALDH1A1L3MBTL1NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181612-A1 POLYMER CONTAINING TRIAZINE RING AND COMPOSITION CONTAINING SAME Nissan Chemical Industries, Ltd. (JP) 2017-06-21 EP disclosed