Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027040 | 0.80 | LMNA (0.36) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| SCHEMBL19004891 | 0.77 | KMT2A (0.38) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| SCHEMBL18986106 | 0.71 | MAPT (0.55) | KMT2ACYP3A4ALOX15HSD17B10NPSR1 | |
| SCHEMBL23605461 | 0.65 | KMT2A (0.37) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| Hydrochloric Acid SCHEMBL23579556 | 0.64 | KMT2A (0.36) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| SCHEMBL19005212 | 0.59 | KIT (0.41) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| SCHEMBL28797149 | 0.59 | ALOX15 (0.59) | KMT2APIK3CGEGFRPIK3CDABL1 | |
| SCHEMBL17651915 | 0.58 | EGFR (0.50) | PIK3CGEGFRPIK3CDABL1HCK | |
| SCHEMBL1650843 | 0.58 | KMT2A (0.33) | KMT2ANPSR1NCOA1NCOA3 | |
| SCHEMBL17689693 | 0.58 | KDM4E (0.62) | PIK3CGEGFRPIK3CDABL1HCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |