SCHEMBL1900496

SCHEMBL1900496

C=C(C)c1cc(Cc2cc(C(C)C)ccc2O)c(O)c(Cc2cc(C(C)C)ccc2O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.45
HIF1A Q16665 3/20 0.41
RNASEH1 O60930 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 3/20 0.40
ALDH1A1 P00352 2/20 0.40
ALOX12 P18054 2/20 0.40
GAA P10253 2/20 0.40
LMNA P02545 3/20 0.39
TSHR P16473 1/20 0.39
TRPA1 O75762 1/20 0.38
PTGS1 P23219 1/20 0.38
CACNA1C Q13936 1/20 0.38
HSP90AA1 P07900 2/20 0.35
HSP90AB1 P08238 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
SLC22A1 O15245 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27842340 0.91 HTT (0.42) AMY1AHIF1ARNASEH1HTTALDH1A1
SCHEMBL1345304 0.86 AMY1A (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL3812859 0.86 AMY1A (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL1345703 0.86 AMY1A (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL1345461 0.86 AMY1A (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL1345280 0.86 AMY1A (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL50460 0.82 ALDH1A1 (0.55) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL1447186 0.81 AMY1A (0.69) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL15662983 0.75 AMY1A (0.58) AMY1AHIF1ARNASEH1CYP2C9CYP2C19
SCHEMBL12035991 0.74 ALDH1A1 (0.47) HIF1ARNASEH1HTTALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850032-B1 POLYARYLENE ETHER BASF SE (DE) 2022-05-25 EP disclosed
EP-3850031-B1 POLYARYLENE ETHER COPOLYMER BASF SE (DE) 2022-05-25 EP disclosed
US-20220056216-A1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2022-02-24 US disclosed
US-20220033583-A1 POLYARYLENE ETHER BASF SE (DE) 2022-02-03 US disclosed
EP-3850031-A1 POLYARYLENE ETHER COPOLYMER BASF SE (DE) 2021-07-21 EP disclosed
EP-3850033-A1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2021-07-21 EP disclosed
EP-3850032-A1 POLYARYLENE ETHER BASF SE (DE) 2021-07-21 EP disclosed
CN-112673052-A Polyarylene ether sulfones 巴斯夫欧洲公司 2021-04-16 CN disclosed
CN-112673049-A Poly (arylene ether) copolymer 巴斯夫欧洲公司 2021-04-16 CN disclosed
CN-112673051-A Poly (arylene ether) 巴斯夫欧洲公司 2021-04-16 CN disclosed
US-20100197859-A1 BLENDS FROM BRANCHED POLYARYL ETHERS AND HYDROPHILIC POLYMERS BASF SE (DE) 2010-08-05 US disclosed
EP-2190924-A1 BLENDS FROM BRANCHED POLYARYL ETHERS AND HYDROPHILIC POLYMERS Basf Se (DE) 2010-06-02 EP disclosed
WO-2010046328-A1 BRANCHED POLYARYLENE ETHERS AND THERMOPLASTIC MOLDING COMPOUNDS CONTAINING SAID ETHERS BASF SE (DE) 2010-04-29 WO disclosed
WO-2009030620-A1 BLENDS FROM BRANCHED POLYARYL ETHERS AND HYDROPHILIC POLYMERS BASF SE (DE) 2009-03-12 WO disclosed
EP-1681311-B1 Branched sulfonated polyarylether BASF AG (DE) 2007-11-28 EP disclosed
EP-1681311-A1 Functionalized polyarylether BASF AKTIENGESELLSCHAFT (DE) 2006-07-19 EP disclosed
US-20060155097-A1 Functionalized polyaryl ethers BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 US disclosed
US-4152367-A RESISTANCE TO UNSATURATED POLYESTER RESINS BAYER AKTIENGESELLSCHAFT (DE) 1979-05-01 US disclosed
EP-0000732-A1 Blends of reticulated polyarylsulfones and polycarbonates and their application during the manufacture of extruded films BAYER AG (DE) 1979-02-21 EP disclosed
US-3960815-A DIELECTRICS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed