Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.80 |
| ▸ | HPGD | P15428 | 6/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | DDO | Q99489 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284596 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL12204302 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL2754183 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL15375702 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL2500290 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL3451421 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8444672 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8440798 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8445875 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8445695 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130309697-A1 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | MITCHELL MATTHEW W (US) | 2013-11-21 | — | — | US | disclosed |
| US-8518650-B2 | Biomarkers for prostate cancer and methods using the same | METABOLON, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2011055987-A2 | METHOD FOR SCREENING OF QUORUM SENSING INHIBITORS | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-05-12 | — | — | WO | disclosed |
| US-20100292331-A1 | Biomarkers for Prostate Cancer and Methods Using the Same | METABALON, INC. (US) | 2010-11-18 | — | — | US | disclosed |