Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441371 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8440798 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8444727 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8444672 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8445695 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8442541 | 1.00 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL4921978 | 0.98 | KDM4E (0.70) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8998008 | 0.93 | KDM4E (0.72) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8552151 | 0.87 | ALDH1A1 (0.71) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL31091563 | 0.85 | CHRNB2 (0.59) | KDM4EPOLBALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5873932-A | BLENDING AN ELECTRON DONATING COMPOUND, AN ELECTRON ACCEPTING COMPOUND, A METACHROMATIC TEMPERATURE ADJUSTER, AN ELECTRON ACCEPTING, LIGHT-FASTNESS PROVIDING AGENT | THE PILOT INK CO., LTD. (JP) | 1999-02-23 | — | — | US | disclosed |