SCHEMBL19005565

SCHEMBL19005565

c1cn2nc3n(c2n1)CCNC3

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19005547 0.73
SCHEMBL109208 0.67
SCHEMBL19005531 0.67
Hydrochloric Acid SCHEMBL20601766 0.66 KDM4E (0.38) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL3353160 0.66 KDM4E (0.38) KDM4EALDH1A1
SCHEMBL19005564 0.63 HTR2C (0.32) KDM4E
SCHEMBL27957909 0.62 MCHR1 (0.35) KDM4EALDH1A1
SCHEMBL107330 0.61 HTR2A (0.36)
SCHEMBL22314692 0.61 SOD3 (0.33)
SCHEMBL928582 0.61 HTR2A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017101796-A1 PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2017-06-22 WO disclosed