SCHEMBL1900605

SCHEMBL1900605

CC(C)(Cl)O[SiH2]OC(C)(C)Cl

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474807 0.75 ALDH1A1 (0.36) TSHR
SCHEMBL9782854 0.74
SCHEMBL211973 0.72 TSHR (0.31) TSHR
Butane SCHEMBL2503526 0.65
SCHEMBL5049758 0.61 TSHR (0.31) TSHR
SCHEMBL1394215 0.61
SCHEMBL7028983 0.61
SCHEMBL6910761 0.61
SCHEMBL477927 0.59
SCHEMBL9901746 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110172367-A1 Grafted Polyethylene DOW CORNING LIMITED (GB) 2011-07-14 US disclosed
EP-2318447-A1 GRAFTED POLYETHYLENE Dow Corning Corporation (US) 2011-05-11 EP disclosed
WO-2010000477-A1 GRAFTED POLYETHYLENE DOW CORNING CORPORATION (US) 2010-01-07 WO disclosed