SCHEMBL19006130

SCHEMBL19006130

CCCCC=C/C(=C/CCCC)N(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
PPARG P37231 2/20 0.33
PPARA Q07869 2/20 0.33
SPHK2 Q9NRA0 2/20 0.32
SPHK1 Q9NYA1 2/20 0.32
PTPN1 P18031 1/20 0.32
CETP P11597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23139471 0.72 CHRNB2 (0.47) ALDH1A1F7F3PPARGPPARA
SCHEMBL2957252 0.71
SCHEMBL2957251 0.71
SCHEMBL10599906 0.71 EP300 (0.44) ALDH1A1TSHRF7F3PPARG
SCHEMBL10599903 0.71 EP300 (0.44) ALDH1A1TSHRF7F3PPARG
SCHEMBL4641972 0.70 TSHR (0.38) ALDH1A1TSHRF7F3
SCHEMBL9850727 0.69 EP300 (0.47) TSHRF7F3PPARGPPARA
SCHEMBL9850729 0.69 EP300 (0.47) TSHRF7F3PPARGPPARA
SCHEMBL10345673 0.69 EP300 (0.47) TSHRF7F3PPARGPPARA
SCHEMBL20199395 0.69 EP300 (0.40) ALDH1A1TSHRF7F3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102893-A1 WATER-SOLUBLE DERIVATIVES OF 3,5-DIPHENYL-DIAZOLE COMPOUNDS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2017-06-22 WO disclosed