Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18370658 | 0.75 | — | — | |
| SCHEMBL13625561 | 0.75 | — | — | |
| SCHEMBL13625589 | 0.75 | — | — | |
| SCHEMBL20143905 | 0.74 | NPC1 (0.40) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL21626881 | 0.73 | — | — | |
| SCHEMBL11703996 | 0.73 | — | — | |
| SCHEMBL8811631 | 0.71 | LMNA (0.39) | ALDH1A1TSHR | |
| SCHEMBL1250524 | 0.71 | — | — | |
| SCHEMBL20649365 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL11496586 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |