Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.84 |
| ▸ | FURIN | P09958 | 1/20 | 0.84 |
| ▸ | AOC1 | P19801 | 1/20 | 0.84 |
| ▸ | SAT1 | P21673 | 1/20 | 0.84 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.84 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18999171 | 0.93 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL120719 | 0.91 | TMPRSS2 (1.00) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL871301 | 0.91 | TMPRSS2 (1.00) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL22491199 | 0.90 | TMPRSS2 (0.96) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL22491202 | 0.90 | TMPRSS2 (0.96) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL13836545 | 0.86 | TMPRSS2 (0.82) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL12348395 | 0.84 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL19006339 | 0.84 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL18999169 | 0.84 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL17469779 | 0.82 | TMPRSS2 (0.66) | TMPRSS2FURINAOC1SAT1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174620-A1 | LINKED DIARYL COMPOUNDS WITH ANTICANCER PROPERTIES AND METHODS OF USING THE SAME | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174620-A1 | LINKED DIARYL COMPOUNDS WITH ANTICANCER PROPERTIES AND METHODS OF USING THE SAME | MCL1, DPYD, TOP2B | TMPRSS2 3385/4885FURIN 3596/4885AOC1 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.