Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 1.00 |
| ▸ | FURIN | P09958 | 1/20 | 1.00 |
| ▸ | AOC1 | P19801 | 1/20 | 1.00 |
| ▸ | SAT1 | P21673 | 1/20 | 1.00 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diminazene SCHEMBL120719 | 1.00 | TMPRSS2 (1.00) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL22491202 | 0.98 | TMPRSS2 (0.96) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL22491199 | 0.98 | TMPRSS2 (0.96) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL18999169 | 0.92 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL12348395 | 0.92 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL19006339 | 0.92 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL19006330 | 0.91 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL18999171 | 0.91 | TMPRSS2 (0.84) | TMPRSS2FURINAOC1SAT1ACE2 | |
| Diminazene SCHEMBL13836545 | 0.91 | TMPRSS2 (0.82) | TMPRSS2FURINAOC1SAT1ACE2 | |
| SCHEMBL22670488 | 0.89 | TMPRSS2 (0.79) | TMPRSS2FURINAOC1SAT1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10203334-B2 | Methods and compositions related to nucleic acid binding assays | Nubad, LLC (US) | 2019-02-12 | — | — | US | claimed |
| US-20160282357-A1 | METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS | Nubad, LLC | 2016-09-29 | — | — | US | claimed |
| US-9017943-B2 | Methods and compositions related to nucleic acid binding assays | NUBAD LLC (US) | 2015-04-28 | — | — | US | claimed |
| US-20140330001-A1 | METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS | Nubad, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-20140024137-A1 | METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS | NUBAD LLC | 2014-01-23 | — | — | US | claimed |
| WO-2013083813-A2 | MODULATORS OF SPERMINE/SPERMIDINE N'-ACETYLTRANSFERASE (SSAT) AND SSAT ASSOCIATED PROTEINS FOR USE IN PREVENTION OR TREATMENT OF RHEUMATOID ARTHRITIS | Universität Zürich (CH) | 2013-06-13 | — | — | WO | claimed |
| US-20100323993-A1 | USES OF PENTAMIDINE AND RELATED COMPOUNDS | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON | 2010-12-23 | — | — | US | claimed |
| WO-2025245089-A1 | PROCESSES FOR PREPARING TETRALIN COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-20250288613-A1 | COMPOSITIONS AND METHODS TARGETING SAT1 FOR ENHANCING ANTI-TUMOR IMMUNITY DURING TUMOR PROGRESSION | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2025-09-18 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118632835-A | Tryptamine compositions and methods | 赛本爱尔兰有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20050014708-A1 | Inhibition of viral replication by targeting RNA-DNA complexes | UNIVERSITY OF MEDICINE AND DENISTRY OF NEW JERSEY | 2005-01-20 | — | — | US | disclosed |
| US-20030069194-A1 | Inhibition of viral replication by targeting RNA-DNA complexes | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | TMPRSS2 3449/4885FURIN 2261/4885AOC1 2297/4885 |
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | DDB1, LIG3, MSH2 | TMPRSS2 2264/4885FURIN 3595/4885AOC1 3751/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | TMPRSS2 219/4885FURIN 158/4885AOC1 2396/4885 |
| US-20100323993-A1 | USES OF PENTAMIDINE AND RELATED COMPOUNDS | MBNL1, MTPN, RRBP1 | TMPRSS2 3609/4885FURIN 3879/4885AOC1 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.