SCHEMBL19006416

SCHEMBL19006416

Cc1ccc2c(c1)C(=O)/C(=C1\Nc3ccc(C)cc3C1=O)N2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROS1 P08922 1/20 0.55
CDK5 Q00535 1/20 0.55
ACVR1 Q04771 1/20 0.55
LRRK2 Q5S007 1/20 0.55
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
GAA P10253 1/20 0.47
CSNK1G1 Q9HCP0 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
TGM2 P21980 5/20 0.46
CES1 P23141 3/20 0.46
ELANE P08246 1/20 0.45
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
RET P07949 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13892935 0.91 CDK5 (0.60) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL18947125 0.85 CA1 (0.46) ROS1CDK5ACVR1LRRK2CA1
SCHEMBL281743 0.85 ROS1 (0.67) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL29657257 0.85 ROS1 (0.67) ROS1CDK5ACVR1LRRK2ALDH1A1
Nitrogen SCHEMBL27949798 0.82 ROS1 (0.62) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL14867083 0.80 ALDH1A1 (0.53) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL3742863 0.80 ROS1 (0.51) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL29194154 0.80 ROS1 (0.51) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL16601853 0.80 CSNK1G1 (0.57) ROS1CDK5ACVR1LRRK2ALDH1A1
SCHEMBL13879091 0.77 ACVR1 (0.60) ROS1CDK5ACVR1LRRK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3182501-B1 ELECTROLYTE FOR NONAQUEOUS SECONDARY BATTERY AND NONAQUEOUS SECONDARY BATTERY USING THE SAME AIST (JP) 2020-07-15 EP disclosed
EP-3182501-A1 ELECTROLYTE FOR NONAQUEOUS SECONDARY CELL AND NONAQUEOUS SECONDARY CELL USING SAME National Institute of Advanced Industrial Science and Technology (JP) 2017-06-21 EP disclosed