Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROS1 | P08922 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 5/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699415 | 0.85 | MAOA (0.44) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL29657257 | 0.82 | ROS1 (0.67) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL281743 | 0.82 | ROS1 (0.67) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL19006416 | 0.80 | ROS1 (0.55) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| Nitrogen SCHEMBL27949798 | 0.78 | ROS1 (0.62) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL29194154 | 0.77 | ROS1 (0.51) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL14867083 | 0.77 | ALDH1A1 (0.53) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| Acetamide SCHEMBL27380996 | 0.73 | ROS1 (0.56) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL13892935 | 0.73 | CDK5 (0.60) | ROS1CDK5ACVR1LRRK2ALDH1A1 | |
| SCHEMBL28202262 | 0.71 | MAOA (0.61) | ACVR1LRRK2ALDH1A1KDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806559-A | Benzothiazepine bridged ring compound and preparation method thereof | 天津理工大学 | 2023-03-17 | — | — | CN | disclosed |
| US-7829567-B2 | Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-09 | — | — | US | disclosed |
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | IMPA1, IMPDH1, IPO5 | ROS1 1395/4885CDK5 1142/4885ACVR1 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.