⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22535894 | 0.94 | — | — | |
| SCHEMBL3647508 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL30187467 | 0.92 | KDM4E (0.95) | — | |
| SCHEMBL4079339 | 0.92 | TP53 (1.00) | — | |
| SCHEMBL4078170 | 0.92 | TP53 (1.00) | — | |
| SCHEMBL23270700 | 0.92 | TP53 (1.00) | — | |
| SCHEMBL133228 | 0.92 | TP53 (1.00) | — | |
| SCHEMBL5228082 | 0.92 | TP53 (1.00) | — | |
| Hydrochloric Acid SCHEMBL19642704 | 0.92 | KDM4E (0.95) | — | |
| Hydrochloric Acid SCHEMBL160732 | 0.90 | KDM4E (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213458-A | Cyclobutylamine-terminated distearoyl phosphatidylcholine and preparation method thereof | 硅羿科技（上海）有限公司 | 2022-03-22 | — | — | CN | claimed |
| WO-2025111492-A1 | INHIBITORS OF PARG | 858 THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| US-12312292-B2 | Long chain alkyl esteramine lipid compound, preparation method therefor and application thereof in nucleic acid delivery | RINUAGENE BIOTECHNOLOGY CO., LTD. (CN) | 2025-05-27 | — | — | US | disclosed |
| US-20240018094-A1 | LONG CHAIN ALKYL ESTERAMINE LIPID COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN NUCLEIC ACID DELIVERY | RINUAGENE BIOTECHNOLOGY CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| WO-2023222081-A1 | LONG-CHAIN ALKYL ESTER AMINE LIPID COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN NUCLEIC ACID DELIVERY | 仁景(苏州)生物科技有限公司 | 2023-11-23 | — | — | WO | disclosed |
| CN-115073316-B | Long-chain alkyl ester amine lipid compound, preparation method thereof and application thereof in nucleic acid delivery | 仁景(苏州)生物科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115073316-A | Long-chain alkyl ester amine lipid compound, preparation method thereof and application thereof in nucleic acid delivery | 仁景(苏州)生物科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114213458-A | Cyclobutylamine-terminated distearoyl phosphatidylcholine and preparation method thereof | 硅羿科技（上海）有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114213458-A | Cyclobutylamine-terminated distearoyl phosphatidylcholine and preparation method thereof | 硅羿科技（上海）有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108137606-B | Short-acting benzodiazepine derivatives, method for the production thereof and use thereof | 四川科伦博泰生物医药股份有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-106892924-B | Short-acting benzodiazepine derivatives, method for the production thereof and use thereof | 四川科伦博泰生物医药股份有限公司 | 2021-01-08 | — | — | CN | disclosed |
| US-20180312511-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2018-11-01 | — | — | US | disclosed |
| EP-3363801-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2018-08-22 | — | — | EP | disclosed |
| CN-108137606-A | Short-acting benzodiazepine * * derivatives, Its Preparation Method And Use | 四川科伦博泰生物医药股份有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-106892924-A | Short-acting benzodiazepine * * derivatives, Its Preparation Method And Use | 四川科伦博泰生物医药股份有限公司 | 2017-06-27 | — | — | CN | disclosed |
| WO-2017101808-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |