Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006969 | 0.82 | HDAC3 (0.40) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22914712 | 0.78 | KDM4E (0.41) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24585190 | 0.76 | MAPT (0.36) | EGFRERBB2KDRLMNAMEN1 | |
| SCHEMBL19006966 | 0.76 | EGFR (0.53) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19736801 | 0.76 | HDAC1 (0.57) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24584631 | 0.76 | KDM4E (0.42) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24585193 | 0.75 | KDM4E (0.39) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24585191 | 0.75 | KDM4E (0.39) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19737040 | 0.72 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL24584632 | 0.71 | KDM4E (0.36) | EGFRERBB2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181554-A1 | QUINAZOLINE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |