Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 10/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24585191 | 0.93 | KDM4E (0.39) | KDM4EMAPTEGFRERBB2HDAC3 | |
| SCHEMBL22914712 | 0.87 | KDM4E (0.41) | KDM4EMAPTEGFRERBB2HDAC3 | |
| SCHEMBL24584631 | 0.86 | KDM4E (0.42) | KDM4EMAPTEGFRERBB2HDAC3 | |
| SCHEMBL24584632 | 0.80 | KDM4E (0.36) | KDM4EMAPTEGFRERBB2ERBB4 | |
| SCHEMBL19737040 | 0.78 | EGFR (0.59) | EGFRERBB2ERBB4SRC | |
| SCHEMBL24585190 | 0.78 | MAPT (0.36) | KDM4EMAPTEGFRERBB2IDO1 | |
| SCHEMBL19006648 | 0.75 | EGFR (0.47) | MAPTEGFRERBB2HDAC3HDAC4 | |
| SCHEMBL19736796 | 0.71 | EGFR (0.60) | EGFRERBB2ERBB4ERBB3ABL1 | |
| SCHEMBL19737042 | 0.70 | EGFR (0.62) | EGFRERBB2ERBB4ERBB3ABL1 | |
| SCHEMBL18632984 | 0.70 | EGFR (0.64) | EGFRERBB2ERBB4ERBB3DUS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022137240-A1 | METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-06-30 | — | — | WO | disclosed |