Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24584632 | 0.87 | KDM4E (0.36) | KDM4EMAPTGAAIDO1TDO2 | |
| SCHEMBL24585193 | 0.86 | KDM4E (0.39) | KDM4EMAPTGAAIDO1TDO2 | |
| SCHEMBL24585191 | 0.86 | KDM4E (0.39) | KDM4EMAPTGAAIDO1TDO2 | |
| SCHEMBL22914712 | 0.84 | KDM4E (0.41) | KDM4EMAPTGAAIDO1TDO2 | |
| SCHEMBL24585190 | 0.79 | MAPT (0.36) | KDM4EMAPTIDO1TDO2MEN1 | |
| SCHEMBL19737040 | 0.76 | EGFR (0.59) | EGFRERBB2ERBB4 | |
| SCHEMBL19006648 | 0.76 | EGFR (0.47) | MAPTMEN1KMT2AEGFRERBB2 | |
| SCHEMBL19736796 | 0.69 | EGFR (0.60) | EGFRERBB2ERBB4ERBB3 | |
| SCHEMBL24584630 | 0.69 | EGFR (0.71) | EGFRERBB2ERBB4HDAC3HDAC4 | |
| SCHEMBL18632984 | 0.69 | EGFR (0.64) | EGFRERBB2ERBB4ERBB3DUS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022137240-A1 | METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-06-30 | — | — | WO | disclosed |