SCHEMBL19006669

SCHEMBL19006669

C=C(C)CCCNC(=C)CCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 1/20 0.42
CASP2 P42575 1/20 0.41
EPHX1 P07099 6/20 0.41
FAAH O00519 6/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
NAAA Q02083 1/20 0.39
PLA2G2A P14555 2/20 0.39
DNM1 Q05193 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22418273 0.96 CASP2 (0.46) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL24483714 0.92 CASP2 (0.41) CASP2EPHX1FAAHZDHHC20ZDHHC2
SCHEMBL24483720 0.92 CASP2 (0.41) CASP2EPHX1FAAHZDHHC20ZDHHC2
SCHEMBL22447142 0.88 EPHX1 (0.50) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL21076334 0.88 EPHX1 (0.50) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL19336122 0.88 EPHX1 (0.50) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL20903683 0.88 EPHX1 (0.52) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL24041036 0.88 EPHX1 (0.52) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL21527587 0.88 EPHX1 (0.52) PLA2G4ACASP2EPHX1FAAHZDHHC20
SCHEMBL18965287 0.88 EPHX1 (0.52) PLA2G4ACASP2EPHX1FAAHZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934567-B1 EXENDIN-4 DERIVATIVES AS DUAL GLP1/GIP- OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS SANOFI SA (FR) 2018-05-09 EP disclosed
EP-2934568-B1 DUAL GLP1/GIP OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS SANOFI SA (FR) 2017-10-18 EP disclosed
EP-2934566-B1 EXENDIN-4 DERIVATIVES AS DUAL GLP1/GIP OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS SANOFI SA (FR) 2017-06-21 EP disclosed