Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006562 | 0.89 | ADRA1A (0.34) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL24127683 | 0.89 | ADRA1A (0.36) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL19006744 | 0.88 | BRD4 (0.34) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL1539510 | 0.86 | KDM4E (0.38) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL30238446 | 0.86 | KDM4E (0.38) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL19006558 | 0.86 | ALDH1A1 (0.35) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL20473280 | 0.86 | ALDH1A1 (0.35) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL17244393 | 0.86 | KDM4E (0.35) | BRD4ADRA1AKDM4EMEN1NPC1 | |
| SCHEMBL21454863 | 0.85 | KDM4E (0.36) | BRD4KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL18513428 | 0.85 | KDM4E (0.35) | BRD4ADRA1AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101808-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |