Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473253 | 0.90 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL19006767 | 0.89 | CYP1A2 (0.38) | BRD4 | |
| SCHEMBL19006568 | 0.89 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL20473269 | 0.89 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL14328999 | 0.88 | GABRA5 (0.48) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL20473339 | 0.83 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL20473218 | 0.83 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL19006652 | 0.83 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL20473268 | 0.81 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL19006524 | 0.81 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101808-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |