Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902595 | 0.81 | POLB (0.50) | SMN1; SMN2TDP1L3MBTL1KMT2AMAPT | |
| SCHEMBL1411430 | 0.76 | HSD17B10 (0.53) | SMN1; SMN2TDP1L3MBTL1CYP2C9KMT2A | |
| SCHEMBL20773262 | 0.71 | EGFR (0.40) | CYP1A2CYP3A4CYP2C19HPGDALDH1A1 | |
| SCHEMBL29587981 | 0.71 | SLC1A2 (0.64) | SMN1; SMN2TDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL21654554 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2TDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL1411315 | 0.70 | PIEZO1 (0.31) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19821083 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2TDP1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9885799 | 0.69 | — | — | |
| SCHEMBL1411566 | 0.69 | PIEZO1 (0.49) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1411043 | 0.69 | NPC1 (0.42) | SMN1; SMN2L3MBTL1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |