SCHEMBL19007477

SCHEMBL19007477

CCn1cc([C@@H]2O[C@H](COP(=O)(Cl)Cl)C(O)C2O)c(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ P2RY6 Q15077 13/20 0.42
▸ P2RY14 Q15391 5/20 0.42
▸ DNPH1 O43598 1/20 0.42
▸ EIF4E P06730 1/20 0.42
▸ UMPS P11172 1/20 0.41
▸ NT5E P21589 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17210975 1.00 P2RY6 (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL15810717 1.00 P2RY6 (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL18852473 1.00 P2RY6 (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL19007491 0.92 EIF4E (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL15810660 0.92 EIF4E (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL17210978 0.92 EIF4E (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL18852524 0.92 EIF4E (0.42) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL18289441 0.90 P2RY6 (0.41) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL18289614 0.90 P2RY6 (0.41) P2RY6P2RY14DNPH1EIF4EUMPS
SCHEMBL18870661 0.89 P2RY6 (0.43) P2RY6P2RY14DNPH1EIF4EUMPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190255194-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX INC (US) 2019-08-22 — — US disclosed
EP-2931319-B1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX INC (US) 2019-08-21 — — EP disclosed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190255194-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 P2RY6 2112/4885P2RY14 2371/4885DNPH1 2277/4885
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 P2RY6 2112/4885P2RY14 2371/4885DNPH1 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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