Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 13/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.40 |
| ▸ | EIF4E | P06730 | 2/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.39 |
| ▸ | UMPS | P11172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289614 | 1.00 | P2RY6 (0.41) | P2RY6P2RY14EIF4EDNPH1UMPS | |
| SCHEMBL17210975 | 0.90 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1UMPS | |
| SCHEMBL18852473 | 0.90 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1UMPS | |
| SCHEMBL19007477 | 0.90 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1UMPS | |
| SCHEMBL15810717 | 0.90 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1UMPS | |
| SCHEMBL19007894 | 0.88 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1 | |
| SCHEMBL15810832 | 0.88 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1 | |
| SCHEMBL18158964 | 0.88 | P2RY6 (0.42) | P2RY6P2RY14EIF4EDNPH1 | |
| SCHEMBL18289613 | 0.83 | P2RY6 (0.49) | P2RY6EIF4EDNPH1UMPS | |
| SCHEMBL18289442 | 0.83 | P2RY6 (0.49) | P2RY6EIF4EDNPH1UMPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354493-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNATX, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160354492-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160354490-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160354490-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354492-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RY6 1545/4885P2RY14 2361/4885EIF4E 2419/4885 |
| US-20160354490-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RY6 1545/4885P2RY14 2361/4885EIF4E 2419/4885 |
| US-20160354493-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | P2RY6 1545/4885P2RY14 2361/4885EIF4E 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.