SCHEMBL19007490

SCHEMBL19007490

CCCn1cc([C@@H]2O[C@H](CO)C(O)C2O)c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.44
TK2 O00142 5/20 0.41
TK1 P04183 1/20 0.40
SLC5A2 P31639 3/20 0.39
P2RY2 P41231 1/20 0.39
SLC28A1 O00337 1/20 0.38
SLC28A2 O43868 1/20 0.38
SLC29A1 Q99808 1/20 0.38
SLC28A3 Q9HAS3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18870659 1.00 PYGM (0.44) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL17210982 1.00 PYGM (0.44) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL15810682 1.00 PYGM (0.44) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL15798586 1.00 PYGM (0.44) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL29135401 0.93 TK2 (0.43) PYGMTK2TK1SLC5A2
SCHEMBL28358456 0.91 CYP1A2 (0.49) PYGMTK2
SCHEMBL18852463 0.90 PYGM (0.45) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL15798320 0.90 PYGM (0.45) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL15810644 0.90 PYGM (0.45) PYGMTK2TK1SLC5A2P2RY2
SCHEMBL17210979 0.90 PYGM (0.45) PYGMTK2TK1SLC5A2P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014770-A1 MODIFIED RNA FOR PREPARING MRNA VACCINE AND THERAPEUTIC AGENT 엠큐렉스 주식회사 2024-01-18 WO disclosed
US-20190255194-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX INC (US) 2019-08-22 US disclosed
EP-2931319-B1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX INC (US) 2019-08-21 EP disclosed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190255194-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 PYGM 2038/4885TK2 305/4885TK1 535/4885
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 PYGM 2038/4885TK2 305/4885TK1 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.