SCHEMBL19007835

SCHEMBL19007835

Cc1ccc2c(c1)ncc1cccnc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
CCR1 P32246 4/20 0.47
CCR8 P51685 4/20 0.47
CCR5 P51681 3/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
PSMD14 O00487 1/20 0.44
COPS5 Q92905 1/20 0.44
KDM4E B2RXH2 3/20 0.41
CYP1A2 P05177 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
HSP90AA1 P07900 2/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 2/20 0.40
GMNN O75496 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19007836 0.87 ALDH1A1 (0.56) ALDH1A1CCR1CCR8CCR5LMNA
SCHEMBL22356919 0.80 KDM4E (0.51) ALDH1A1CCR1CCR8CCR5LMNA
SCHEMBL22237863 0.80 LMNA (0.47) ALDH1A1CCR1CCR8CCR5LMNA
SCHEMBL19794329 0.80 CYP1A2 (0.56) ALDH1A1LMNAKDM4ECYP1A2HTT
SCHEMBL19007832 0.80 KDM4E (0.53) ALDH1A1CCR1CCR8CCR5L3MBTL1
SCHEMBL12346092 0.77 CCR1 (0.61) ALDH1A1CCR1CCR8CCR5LMNA
SCHEMBL13915654 0.77 KDM4E (0.62) ALDH1A1LMNAL3MBTL1KDM4ECYP1A2
SCHEMBL2230568 0.77 ALDH1A1 (0.56) ALDH1A1L3MBTL1KDM4ECYP1A2HTR1A
SCHEMBL4164142 0.77 LMNA (0.66) ALDH1A1CCR1CCR8CCR5LMNA
SCHEMBL19007834 0.77 KDM4E (0.53) ALDH1A1CCR1CCR8CCR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-20180097186-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-05 US disclosed
US-9887244-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-06 US disclosed
US-20170373267-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-12-28 US disclosed
US-20170331048-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170294613-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170294489-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170244043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-24 US disclosed
US-20170179204-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180097186-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME C1S, C1R, C9 ALDH1A1 1286/4885CCR1 57/4885CCR8 525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.