Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581791 | 0.87 | HPGD (0.48) | HPGDALDH1A1SMN1; SMN2IDO1GAA | |
| SCHEMBL5958730 | 0.85 | HPGD (0.50) | HPGDCA1CA2SMN1; SMN2LMNA | |
| SCHEMBL77911 | 0.85 | HPGD (0.50) | HPGDCA1CA2SMN1; SMN2LMNA | |
| SCHEMBL77912 | 0.85 | HPGD (0.50) | HPGDCA1CA2SMN1; SMN2LMNA | |
| SCHEMBL18078309 | 0.85 | ALDH1A1 (0.46) | HPGDALDH1A1SMN1; SMN2IDO1LMNA | |
| SCHEMBL18078308 | 0.85 | ALDH1A1 (0.46) | HPGDALDH1A1SMN1; SMN2IDO1LMNA | |
| SCHEMBL28281679 | 0.83 | CA12 (0.51) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL18073732 | 0.83 | IDO1 (0.46) | HPGDALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL18073731 | 0.83 | IDO1 (0.46) | HPGDALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL15991618 | 0.81 | ALDH1A1 (0.47) | HPGDCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164889-B1 | METHOD TO PRODUCE HIGH MOLECULAR WEIGHT POLYESTER POLYMERS WITH REDUCED ACETALDEHYDE CONTENT | GRUPO PETROTEMEX SA DE CV (MX) | 2017-06-21 | — | — | EP | disclosed |