SCHEMBL19008218

SCHEMBL19008218

C=Cc1ccc(COc2ccc(C3(c4cccc(OCc5ccc(COc6c(C)cc(Oc7c(C)cc(C)c(C)c7C)cc6C)cc5)c4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.33
HIF1A Q16665 1/20 0.33
MAPT P10636 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PDK2 Q15119 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
FFAR1 O14842 1/20 0.30
ALOX5 P09917 1/20 0.30
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860051 0.95 MAPT (0.33) LCKHIF1AMAPTMAOBESR1
SCHEMBL19860052 0.90 MAPT (0.33) LCKHIF1AMAPTESR1ESR2
SCHEMBL19008219 0.89 HIF1A (0.33) LCKHIF1AMAPTMAOAMAOB
SCHEMBL19860053 0.86 MAPT (0.34) LCKHIF1AMAPTMAOAMAOB
SCHEMBL19860050 0.84 PDK2 (0.33) HIF1AMAPTESR1ESR2PDK2
SCHEMBL19017287 0.83 LCK (0.31) LCKHIF1A
SCHEMBL31326063 0.78 KDM4E (0.41) LCKMAPTMAOAMAOBPDK2
SCHEMBL19017222 0.77 NPC1 (0.46) MAPTMAOAMAOBNPC1RAB9A
SCHEMBL19017288 0.77 PPARA (0.33)
SCHEMBL19017284 0.77 LCK (0.32) LCKHIF1AMAPTPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890246-B2 Fluorenylidene-diphenol-containing polyphenylene oxide ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) 2018-02-13 US disclosed
US-20170174835-A1 FLUORENYLIDENE-DIPHENOL-CONTAINING POLYPHENYLENE OXIDE ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) 2017-06-22 US disclosed