SCHEMBL19860050

C=Cc1ccc(COc2ccc(C3(c4ccc(OCc5ccc(COc6c(C)cc(Oc7c(C)cc(C(C)(C)c8cc(C)c(Oc9cc(C)c(OCc%10ccc(COc%11ccc(C%12(c%13ccc(OCc%14ccc(C=C)cc%14)cc%13)c%13ccccc%13-c%13ccccc%13%12)cc%11)cc%10)c(C)c9)c(C)c8)cc7C)cc6C)cc5)cc4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PDK2	Q15119	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	PPARG	P37231	2/20	0.32

▸	PPARA	Q07869	1/20	0.32

▸	ESR1	P03372	1/20	0.31

▸	ESR2	Q92731	1/20	0.31

▸	FFAR1	O14842	1/20	0.31

▸	HIF1A	Q16665	1/20	0.30

▸	MMP2	P08253	1/20	0.30

▸	MMP13	P45452	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19860053	0.92	MAPT (0.34)	PDK2MAPTESR1ESR2FFAR1
SCHEMBL19008219	0.90	HIF1A (0.33)	PDK2MAPTESR1ESR2FFAR1
SCHEMBL19860052	0.88	MAPT (0.33)	PDK2MAPTESR1ESR2FFAR1
SCHEMBL19860051	0.88	MAPT (0.33)	PDK2MAPTESR1ESR2FFAR1
SCHEMBL19008218	0.84	LCK (0.33)	PDK2MAPTESR1ESR2FFAR1
SCHEMBL14749885	0.83	MAPT (0.33)	MAPTPPARGPPARAFFAR1HIF1A
SCHEMBL31326063	0.81	KDM4E (0.41)	PDK2MAPTPPARG
SCHEMBL19017222	0.80	NPC1 (0.46)	MAPT
SCHEMBL19077749	0.80	MAPT (0.35)	MAPTHIF1A
SCHEMBL19017289	0.79	PPARA (0.34)	PDK2MAPTPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9890246-B2	Fluorenylidene-diphenol-containing polyphenylene oxide	ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN)	2018-02-13	—	—	US	disclosed