Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19860050 | 0.92 | PDK2 (0.33) | MAPTESR1ESR2PDK2FFAR1 | |
| SCHEMBL19860051 | 0.91 | MAPT (0.33) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL19860052 | 0.91 | MAPT (0.33) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL19008219 | 0.87 | HIF1A (0.33) | MAPTRAB9ANPC1ESR1ESR2 | |
| SCHEMBL19008218 | 0.86 | LCK (0.33) | MAPTRAB9ANPC1ESR1ESR2 | |
| SCHEMBL19017222 | 0.85 | NPC1 (0.46) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL31326063 | 0.84 | KDM4E (0.41) | MAPTRAB9ASMN1; SMN2MAOAMAOB | |
| SCHEMBL18995993 | 0.82 | NPC1 (0.37) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL19017289 | 0.81 | PPARA (0.34) | MAPTPDK2 | |
| SCHEMBL19017217 | 0.81 | HPGD (0.43) | RAB9ANPC1SMN1; SMN2GRM5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890246-B2 | Fluorenylidene-diphenol-containing polyphenylene oxide | ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) | 2018-02-13 | — | — | US | disclosed |