Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821408 | 0.89 | ALDH1A1 (0.50) | HDAC1HDAC2HDAC6CA14CA12 | |
| SCHEMBL21470872 | 0.87 | HDAC6 (0.50) | HDAC1HDAC2HDAC6ALDH1A1CES2 | |
| SCHEMBL23904398 | 0.83 | HDAC6 (0.41) | HDAC1HDAC2HDAC6CA14CA12 | |
| SCHEMBL28595621 | 0.82 | PHF8 (0.45) | HDAC1HDAC2HDAC6CA14NFKB1 | |
| SCHEMBL17277202 | 0.82 | HDAC6 (0.41) | HDAC1HDAC2HDAC6CA14NFKB1 | |
| SCHEMBL14313313 | 0.81 | HDAC6 (0.37) | HDAC1HDAC2HDAC6CA14CA12 | |
| SCHEMBL21952203 | 0.79 | HDAC6 (0.46) | HDAC1HDAC2HDAC6CA14NFKB1 | |
| SCHEMBL2246456 | 0.79 | HDAC6 (0.41) | HDAC1HDAC2HDAC6CA14CA12 | |
| SCHEMBL8737769 | 0.78 | HDAC6 (0.39) | HDAC1HDAC2HDAC6CA14CA12 | |
| SCHEMBL24737134 | 0.78 | NFKB1 (0.45) | HDAC1HDAC2HDAC6CA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938249-B2 | Anti-amyloid compounds containing benzofurazan | TREVENTIS CORPORATION (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170174641-A1 | ANTI-AMYLOID COMPOUNDS CONTAINING BENZOFURAZAN | TREVENTIS CORPORATION (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174641-A1 | ANTI-AMYLOID COMPOUNDS CONTAINING BENZOFURAZAN | PRNP, PSEN1, APP | HDAC1 1221/4885HDAC2 2588/4885HDAC6 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.