Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646456 | 1.00 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL29257688 | 1.00 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL2067136 | 1.00 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL3293988 | 1.00 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1900915 | 1.00 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL13416816 | 0.82 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL16316581 | 0.82 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL5509761 | 0.82 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL19538503 | 0.82 | TP53 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL14299180 | 0.82 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239988-A | Preparation method and application of heterochiral binuclear Ir (III) metal-organic double-helix structure compound | 大连理工大学 | 2024-06-25 | — | — | CN | claimed |
| CN-114437136-B | Preparation method and application of thiourea functionalized multi-chiral binuclear Ir (III) metal-organic double helix structure | 大连理工大学 | 2023-06-27 | — | — | CN | claimed |
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | YALE UNIVERSITY (US) | 2007-11-08 | — | — | US | claimed |
| EP-1745056-A4 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY CORP (US) | 2007-10-31 | — | — | EP | claimed |
| EP-1745056-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | Yale University Corporation (US) | 2007-01-24 | — | — | EP | claimed |
| US-20060199728-A1 | Enantioselective amination and etherification | YALE UNIVERSITY (US) | 2006-09-07 | — | — | US | claimed |
| WO-2005111050-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY (US) | 2005-11-24 | — | — | WO | claimed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | claimed |
| CN-116606296-B | Electronic transmission material phenanthroline derivative and synthesis and application method thereof | 西安欧得光电材料有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-118239988-A | Preparation method and application of heterochiral binuclear Ir (III) metal-organic double-helix structure compound | 大连理工大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-116606296-A | Electronic transmission material phenanthroline derivative and synthesis and application method thereof | 西安欧得光电材料有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2021223156-A1 | DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2021-11-11 | — | — | WO | disclosed |
| WO-2018060512-A1 | PROCESS FOR PREPARING CHIRAL AMINES | PATHEON AUSTRIA GMBH & CO KG (AT) | 2018-04-05 | — | — | WO | disclosed |
| EP-3301087-A1 | PROCESS FOR PREPARING CHIRAL AMINES | DPx Fine Chemicals Austria GmbH & Co KG (AT) | 2018-04-04 | — | — | EP | disclosed |
| WO-2005111050-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY (US) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005077885-A1 | RUTHENIUM-CATALYZED HYDROAMINATION OF OLEFINS | YALE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |
| US-20030199713-A1 | Catalyst for asymmetric (transfer) hydrogenation | JLL/DELTA DUTCH NEWCO B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| EP-1325013-A2 | CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION | DSM N.V. (NL) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002004466-A2 | CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION | DSM N.V. (NL) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | AKR1C3, PCNA, AKR1C4 | EPHX1 223/4885TP53 1604/4885KDM4E 4148/4885 |
| US-20030199713-A1 | Catalyst for asymmetric (transfer) hydrogenation | MLX, ACSL3, MSL1 | EPHX1 4004/4885TP53 4850/4885KDM4E 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.