Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591062 | 1.00 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1900477 | 1.00 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1305495 | 1.00 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL14119724 | 0.97 | CYP1A2 (0.55) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL19951722 | 0.97 | CYP1A2 (0.55) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL30098259 | 0.97 | CYP1A2 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3253569 | 0.91 | DPP4 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10868139 | 0.91 | TDP1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10866506 | 0.91 | TDP1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13298408 | 0.91 | DPP4 (0.61) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632917-B1 | NOVEL PHASE TRANSFER CATALYSTS | UNIV SINGAPORE (SG) | 2016-04-20 | — | — | EP | disclosed |
| US-20130217889-A1 | NOVEL PHASE TRANSFER CATALYSTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-08-22 | — | — | US | disclosed |
| EP-2146986-B1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | HOFFMANN LA ROCHE (CH) | 2011-06-29 | — | — | EP | disclosed |
| EP-1661903-B1 | NOVEL TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL WITH THE COMPLEX | TAKASAGO PERFUMERY CO LTD (JP) | 2011-05-11 | — | — | EP | disclosed |
| US-7625895-B2 | Diphenyl-dihydro-imidazopyridinones | Hoffmann-Le Roche Inc. (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625895-B2 | Diphenyl-dihydro-imidazopyridinones | Hoffmann-Le Roche Inc. (US) | 2009-12-01 | — | — | US | disclosed |
| US-7473793-B2 | Transition metal (rhodium or ruthenium) complex of a bis(diaryl- or dialicyclylphosphinoaryl) compound and an optionally substituted 1,2-diphenylethylenediamine; hydrogenation catalysts for forming an assymetric alcohol from an assymetric ketone; high optical purity and high yield | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |
| WO-2008125487-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255119-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | DOMINIQUE ROMYR | 2008-10-16 | — | — | US | disclosed |
| US-20080255119-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | DOMINIQUE ROMYR | 2008-10-16 | — | — | US | disclosed |
| US-20080255119-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | DOMINIQUE ROMYR | 2008-10-16 | — | — | US | disclosed |
| EP-1661903-A1 | NOVEL TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL WITH THE COMPLEX | Takasago International Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255119-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | TP53, MDM2, TP53BP1 | CA1 2762/4885CA2 3161/4885CA7 4315/4885 |
| US-20130217889-A1 | NOVEL PHASE TRANSFER CATALYSTS | POLR2B, POLR1A, POLR2A | CA1 2859/4885CA2 4151/4885CA7 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.