SCHEMBL19009235

SCHEMBL19009235

Cc1cccc(-c2cc(-c3cccnc3)cc(-c3cccnc3)c2)n1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.81
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP19A1 P11511 2/20 0.49
CCR1 P32246 1/20 0.48
CCR8 P51685 1/20 0.48
KARS1 Q15046 1/20 0.48
MEN1 O00255 1/20 0.46
PSIP1 O75475 1/20 0.46
AXL P30530 1/20 0.46
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
ALK Q9UM73 1/20 0.45
CYP2E1 P05181 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2B6 P20813 1/20 0.45
CYP17A1 P05093 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3609216 0.90 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL12070462 0.88 CYP19A1 (0.61) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL17532803 0.85 CYP2A6 (0.62) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL17532834 0.85 CYP2A6 (0.62) CYP2A6CYP3A4ALDH1A1CYP19A1KARS1
SCHEMBL21083089 0.85 CYP19A1 (0.59) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL29512051 0.82 CYP2A6 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL21438625 0.82 CYP2A6 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL3421988 0.82 CYP2A6 (0.67) CYP2A6CCR1CCR8
SCHEMBL12925581 0.82 CYP2A6 (0.67) CYP2A6CYP3A4ALDH1A1CYP1A2CYP19A1
SCHEMBL13483700 0.82 CCR1 (0.71) CYP2A6CCR1CCR8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10597403-B2 Condensed cyclic compound, composition including the condensed cyclic compound, organic light-emitting device including the condensed cyclic compound, and method of manufacturing the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-24 US disclosed
US-20170174705-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-22 US disclosed
US-20170174705-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174705-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, C9, CRY2 CYP2A6 1905/4885CYP3A4 1035/4885ALDH1A1 490/4885
US-10597403-B2 Condensed cyclic compound, composition including the condensed cyclic compound, organic light-emitting device including the condensed cyclic compound, and method of manufacturing the organic light-emitting device CRY1, C9, CRY2 CYP2A6 1905/4885CYP3A4 1035/4885ALDH1A1 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.