SCHEMBL19009635

SCHEMBL19009635

c1ccc(-c2cccc(-c3c4ccccc4c(-c4nc5ccccc5c5ccccc45)c4ccccc34)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
LMNA P02545 1/20 0.41
GPR3 P46089 1/20 0.39
DHODH Q02127 4/20 0.39
ADORA2A P29274 2/20 0.39
NUDT1 P36639 1/20 0.39
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PDE10A Q9Y233 3/20 0.38
ACHE P22303 1/20 0.38
PKM P14618 1/20 0.37
GP6 Q9HCN6 1/20 0.37
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12578116 0.88 ADORA2A (0.40) ESR1ESR2LMNADHODHADORA2A
SCHEMBL13614900 0.83 L3MBTL1 (0.51) ESR1ESR2LMNADHODHADORA2A
SCHEMBL12578131 0.83 ESR1 (0.44) ESR1ESR2LMNAADORA2ANUDT1
SCHEMBL29274261 0.82 ESR1 (0.61) ESR1ESR2LMNADHODHADORA2A
SCHEMBL12578121 0.81 LMNA (0.45) ESR1ESR2LMNADHODHADORA2A
SCHEMBL12578127 0.80 ESR1 (0.42) ESR1ESR2DHODHADORA2ANUDT1
SCHEMBL12578109 0.80 ESR1 (0.41) ESR1ESR2LMNADHODHADORA2A
SCHEMBL22956107 0.79 ESR1 (0.41) ESR1ESR2LMNAGPR3ADORA2A
SCHEMBL12578100 0.79 ESR1 (0.46) ESR1ESR2LMNADHODHADORA2A
SCHEMBL12578161 0.78 ESR1 (0.43) ESR1ESR2DHODHADORA2ANUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed