SCHEMBL19010459

SCHEMBL19010459

c1ccc(-c2ccc(N(c3ccc4c(c3)sc3ccccc34)c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
F9 P00740 1/20 0.32
ALOX5 P09917 1/20 0.32
ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19010988 1.00 ALDH1A1 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL24905210 0.99 ALDH1A1 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL19011102 0.95 ALDH1A1 (0.30) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL23382969 0.95 F9 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL19010444 0.95 LIMK1 (0.33) ABCB1
SCHEMBL19011199 0.94 ALDH1A1 (0.31) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL15213611 0.94 ALOX5 (0.32) ALOX5
SCHEMBL24646852 0.93
SCHEMBL25472948 0.93 MAPT (0.31) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25472958 0.93 F9 (0.34) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102064-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed