SCHEMBL190108

SCHEMBL190108

CCC(C)c1ccccc1OO

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
KDM4E B2RXH2 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.47
NISCH Q9Y2I1 1/20 0.47
ALDH1A1 P00352 1/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
KMT2A Q03164 1/20 0.38
RORC P51449 1/20 0.37
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430089 0.86 TSHR (0.45) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL2352057 0.85 TSHR (0.41) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL19355318 0.83 TSHR (0.57) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL7710832 0.83 TSHR (0.57) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL19314294 0.83 TSHR (0.57) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL29657286 0.83 TSHR (0.57) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL6679628 0.83 TSHR (0.57) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL3675728 0.83 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL11692592 0.83 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH
SCHEMBL15515578 0.83 TSHR (0.48) TSHRKDM4EL3MBTL1ATMNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756993-A Preparation method of low-yellowness-index acrylonitrile-butadiene-styrene graft copolymer and ABS rubber powder 万华化学集团股份有限公司 2024-03-26 CN claimed
US-10954180-B2 Process for acid-catalyzed decomposition of aryl α-hydroperoxide with continuous flow tubular reactor Changzhou University (CN) 2021-03-23 US claimed
CN-107922289-B Process for producing cumene and/or sec-butylbenzene using mixed olefin streams as alkylating agents 沙特基础工业全球技术有限公司 2021-01-26 CN claimed
CN-112250609-A Alkylbenzene hydroperoxide production using dispersed bubbles of oxygen-containing gas 沙特基础工业全球技术有限公司 2021-01-22 CN claimed
EP-3186215-B1 ALKYLBENZENE HYDROPEROXIDE PRODUCTION USING DISPERSED BUBBLES OF OXYGEN CONTAINING GAS SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-12-02 EP claimed
EP-3327003-B1 PROCESS FOR CONCENTRATING A MIXTURE CONTAINING ORGANIC HYDROPEROXIDE EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-09-16 EP claimed
US-20200079714-A1 PROCESS FOR ACID-CATALYZED DECOMPOSITION OF ARYL a- HYDROPEROXIDE WITH CONTINUOUS FLOW TUBULAR REACTOR Changzhou University (CN) 2020-03-12 US claimed
US-10414700-B2 Process for producing cumene and/or sec-butylbenzene using a mixed olefins stream as alkylation agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-17 US claimed
EP-3347331-B1 PROCESS FOR PRODUCING CUMENE AND/OR SEC-BUTYLBENZENE USING A MIXED OLEFINS STREAM AS ALKYLATION AGENT SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-08-21 EP claimed
EP-3347331-A1 PROCESS FOR PRODUCING CUMENE AND/OR SEC-BUTYLBENZENE USING A MIXED OLEFINS STREAM AS ALKYLATION AGENT SABIC Global Technologies B.V. (NL) 2018-07-18 EP claimed
US-5334774-A Distillation using addatives, recycling SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-02 US claimed
US-5304684-A Oxidizing sec-butylbenzene to hydroperoxide, concentrating, decomposing, neutralizing, distilling, washing SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1994-04-19 US claimed
US-5298667-A Oxidizing secendory-butylbenzene forming hydroperoxide and exhaust gas, cooling, concentration, washing, decomposing SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-29 US claimed
EP-0578194-A2 Process for producing phenol and methyl ethyl ketone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-01-12 EP claimed
EP-0573070-A2 Process for purifying phenol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-08 EP claimed
EP-0548986-A1 Process for producing phenol and methyl ethyl ketone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-30 EP claimed
US-4617359-A High molecular weight polyacrylamide synthesis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-10-14 US claimed
EP-0008869-B1 PROCESS FOR THE PRODUCTION OF A PHENOL AND A CARBONYL COMPOUND BY THE CATALYSED DECOMPOSITION OF AN AROMATIC HYDROPEROXIDE BP Chemicals Limited (GB) 1983-03-02 EP claimed
US-4246203-A Process for the production of a phenol and a carbonyl compound by the catalyzed decomposition of an aromatic hydroperoxide BP CHEMICALS LIMITED (GB) 1981-01-20 US claimed
EP-0008869-A1 Process for the production of a phenol and a carbonyl compound by the catalysed decomposition of an aromatic hydroperoxide BP Chemicals Limited (GB) 1980-03-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079714-A1 PROCESS FOR ACID-CATALYZED DECOMPOSITION OF ARYL a- HYDROPEROXIDE WITH CONTINUOUS FLOW TUBULAR REACTOR HAO2, AHR, HAO1 TSHR 1982/4885KDM4E 3634/4885L3MBTL1 4789/4885
US-10954180-B2 Process for acid-catalyzed decomposition of aryl α-hydroperoxide with continuous flow tubular reactor HAO2, HAO1, TDO2 TSHR 2083/4885KDM4E 3704/4885L3MBTL1 4811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.