SCHEMBL19010993

SCHEMBL19010993

c1ccc(-c2ccc(-c3ccc(N(c4ccc5c(c4)oc4ccccc45)c4cccc5c4-c4ccccc4C54c5ccccc5-c5ccccc54)cc3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.32
ALOX5 P09917 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
THRB P10828 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19167384 1.00 AHR (0.32) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL15213678 1.00 AHR (0.32) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL15213645 0.99 AHR (0.33) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL24883126 0.98 PLA2G2A (0.31) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL21202779 0.97 AHR (0.30) AHRALOX5MEN1KMT2ATHRB
SCHEMBL24883007 0.97 AHR (0.30) AHRALOX5MEN1KMT2ATHRB
SCHEMBL19010442 0.97 MMP12 (0.34) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL19011099 0.96 MMP12 (0.33) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL19011107 0.96 MMP12 (0.35) AHRALOX5MEN1KMT2AKDM4E
SCHEMBL23383227 0.95 MEN1 (0.32) AHRALOX5MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102064-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed