Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ESR1 | P03372 | 9/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.73 |
| ▸ | ESRRG | P62508 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17915615 | 0.94 | HTR6 (0.75) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL17246776 | 0.91 | HTR6 (0.72) | HTR6LMNAESR1ESR2CYP19A1 | |
| Ospemifene SCHEMBL2231997 | 0.91 | LMNA (0.71) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL5737939 | 0.91 | LMNA (0.71) | HTR6LMNAESR1ESR2CYP19A1 | |
| Ospemifene SCHEMBL948118 | 0.91 | LMNA (0.71) | HTR6LMNAESR1ESR2CYP19A1 | |
| Ospemifene SCHEMBL948120 | 0.91 | LMNA (0.71) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL9098766 | 0.90 | ESR1 (0.90) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL5738182 | 0.90 | LMNA (0.70) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL9098770 | 0.90 | ESR1 (0.90) | HTR6LMNAESR1ESR2CYP19A1 | |
| SCHEMBL906293 | 0.90 | ESR1 (0.90) | HTR6LMNAESR1ESR2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181545-B1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE | SHIONOGI & CO (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-3835285-A1 | METHOD FOR PRODUCING PHENOXYETHANOL DERIVATIVE | Shionogi & Co., Ltd (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3415491-B1 | METHOD FOR PRODUCING PHENOXYETHANOL DERIVATIVE | SHIONOGI & CO (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-3181545-A1 | METHOD FOR PRODUCING TRIPHENYLBUTENE DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2017-06-21 | — | — | EP | disclosed |