Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
| ▸ | GUCY1B2 | O75343 | 16/20 | 0.48 |
| ▸ | GUCY1A2 | P33402 | 16/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 16/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492087 | 0.89 | GUCY1B2 (0.43) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL7497668 | 0.88 | CYP3A4 (0.53) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL18570328 | 0.86 | CYP3A4 (0.52) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL20528787 | 0.84 | ATP4A (0.46) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL16403535 | 0.84 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16399545 | 0.83 | GUCY1B2 (0.54) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL15663508 | 0.83 | GUCY1B2 (0.52) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16402801 | 0.82 | GUCY1B2 (0.53) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16403049 | 0.82 | GUCY1B2 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16402956 | 0.82 | GUCY1B2 (0.46) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914596-B1 | HYDROXY SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE CARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma AG (DE) | 2017-06-21 | — | — | EP | disclosed |